DNA privacy: don't flatter yourself

The secrets contained in our individual genomes are less valuable than we like to believe

IMAGINE donating your DNA to a project aimed at discovering links between genes and diseases. You consent to your genome sequence being released anonymously into the public domain, though you are warned there is a remote possibility that it might one day be possible to link it back to you.

A few years later, that remote possibility comes to pass. How should you feel? This is no longer a hypothetical scenario. About 50 people who participated in a project called 1000 Genomes have been traced (see "Matching names to genes: the end of genetic privacy?").

The researchers' intentions were honourable. They have not revealed these identities, and the original data has been adjusted to make a repeat using the same technique impossible. All they wanted to do was expose privacy issues.

Consider them exposed. It is clear that genomics has entered a new phase, similar to that which social media went through a few years ago, when concerns were raised about people giving away too much personal information.

What happens when the same applies to our DNA? Having your genome open to public scrutiny obviously raises privacy issues. Employers and insurers may be interested. Embarrassing family secrets may be exposed.

But overall, personal genetic information is probably no more revealing than other sorts. In fact there are reasons to believe that it is less so: would an insurance company really go to the trouble of decoding a genome to discover a slightly elevated risk of cancer or Alzheimer's disease?

The available evidence suggests not. In 2006, Harvard University set out to sequence the genomes of 100,000 volunteers and make them publicly available, along with personal information such as names and medical records. One of the goals was to see what happens when such data is open to all. The answer seems to be "not a lot". So far this Personal Genome Project has published 148 people's full genomes. Not one volunteer has reported a privacy issue.

This is not a reason for complacency, but it suggests that our genomic secrets are less interesting to other people than we might like to believe.

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Major floods sweep northeast Australia

SYDNEY: Two people were missing and the body of a third person was recovered from raging floodwaters as severe storms pounded northeastern Australia on Sunday, forcing more than 1,000 to flee their homes.

Army aircraft were deployed in the northern state of Queensland, where storms generated by former tropical cyclone Oswald unleashed punishing rains and localised tornadoes and floodwaters threatened several major towns.

One woman was plucked to safety in Biloela, 600 kilometres northwest of the state capital Brisbane, after she spent eight hours clinging to a tree.

At Gympie, north of Brisbane, three families waited on the roofs of their homes for seven hours before rescue helicopters, hampered by high winds, managed to reach them, town mayor Ron Dyne said.

A 27-year-old man was missing after he tried to cross a swollen creek near Gympie, and state Premier Campbell Newman said there were serious concerns for another young woman.

"Emergency services are searching for a young woman who reportedly drove into waters near Pacific Haven this morning, and we have grave fears for her safety," Newman told reporters.

Separately on Sunday, police said the body of an elderly man who went to check on a yacht had been recovered from waters north of Bundaberg, where the engorged Burnett River broke its banks and was expected to engulf 300 homes.

Bundaberg was among dozens of towns devastated by floods in Queensland two years ago that claimed 35 lives. Newman said residents there were bracing for the river to peak above nine metres, well in excess of the 7.92 metres seen in 2011.

Further north at Gladstone, about 900 homes were evacuated and several towns in the region were already isolated by the rising waters.

Across the state some 58,000 homes were without power and that number was growing by the hour, according to Newman.

"We are right in the middle of this now, I can hear it bucketing down on the roof as we speak," he said.

Authorities warned residents in New South Wales to prepare for possible flash floods and strong winds of up to 100 kilometres per hour on Monday as the storm system moves further south, the AAP news agency reported.

Prime Minister Julia Gillard said the emergency had revived "memories of the floods of two summers ago", which she said were "still fresh".

The Insurance Council of Australia declared a statewide catastrophe, noting that there had already been "severe inundation... in several towns and cities" and that major flood warnings had been issued.

"Unfortunately, this catastrophe declaration is the result of the first cyclone to come close to the coast this season, and the weather bureau has warned it's highly possible we will see more before the end of summer," said council chief Rob Whelan.

At least one international flight was diverted from Brisbane to Sydney due to the high winds and Qantas cancelled a number of domestic services, with the Sunshine Coast regional airport shut down.

A staggering 1-1.5 metres of rain was estimated to have fallen since the storms began.

Cyclones and floods are common in Australia's northeast during the warmer summer months. A massive inundation of Queensland in 2011 killed 35 people and brought Brisbane to a standstill for several days, swamping some 30,000 homes.

Brisbane was expected to be spared the kind of flooding seen two years ago, with officials predicting 3,600 homes and 1,250 businesses will be inundated, none in the central city.

- AFP/de

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Kutcher went on Jobs' fruitarian diet, landed in the hospital

Did the fruit help?

(Credit:
JBeylovesyou/YouTube Screenshot by Chris Matyszczyk/CNET)

Actors are lovely people.

Until they take themselves seriously, that is.

Then, eccentricities are magnified, intentions are doubted and sanity is questioned.

What to make, you see, of Ashton Kutcher's revelation that, in some actorial attempt to be as much like Steve Jobs as he could, he became a fruitcake?

This is the technical term for someone who decides to go on a fruitarian diet, which involves only allowing fruits, nuts, and seeds inside you -- something that Jobs himself tried.

As the entirely unseedy US Weekly digests it, Kutcher was so dedicated to pursuing his craft that pursuing this diet put him in hospital.

I am sure the producers of "jOBS" were delighted with his dedication, as he was sent to ER just two days before shooting started.

More Technically Incorrect

"I was like doubled over in pain and my pancreas levels were completely out of whack, which was completely terrifying, considering everything, Kutcher told US Weekly.

Terrifying, indeed. And, perhaps, not wholly unsurprising.

Still, it doesn't seem to have been as terrifying as playing Jobs.

Kutcher emoted: "It's portraying a guy who just passed away that is really fresh in people's minds, that people are really passionate about, and care about, and have an opinion about -- that's really scary. Especially portraying a guy that I really admire . . . it's terrifying, it's terrifying!"

My colleague Casey Newton, who witnessed the movie on Friday, seems to have been less terrified and more numbed at the experience, although he seemed reasonably enamored of Kutcher's performance.

I'm sure it was the fruit that got him closer to the man.

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Pictures: The Story Behind Sun Dogs, Penitent Ice, and More

Photograph by Art Wolfe, Getty Images

If you want the beauty of winter without having to brave the bone-chilling temperatures blasting much of the United States this week, snuggle into a soft blanket, grab a warm beverage, and curl up with some of these natural frozen wonders.

Nieve penitente, or penitent snow, are collections of spires that resemble robed monks—or penitents. They are flattened columns of snow wider at the base than at the tip and can range in height from 3 to 20 feet (1 to 6 meters). The picture above shows the phenomenon in central Chile. (See pictures of the patterns in snow and ice.)

Nieve penitente tend to form in shallow valleys where the snow is deep and the sun doesn't shine at too steep an angle, said Kenneth Libbrecht, a physicist at the California Institute of Technology in Pasadena who studies ice crystal formation.

As the snow melts, dirt gets mixed in with the runoff and collects in little pools here and there, he said. Since the dirt is darker in color than the surrounding snow, the dirty areas melt faster "and you end up digging these pits," explained Libbrecht.

"They tend to form at high altitude," he said. But other than that, no one really knows the exact conditions that are needed to form penitent snow.

"They're fairly strong," Libbrecht said. "People have found [the spires] difficult to hike through."

—Jane J. Lee

Published January 25, 2013

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Brazil Nightclub Fire: 232 Dead, Hundreds Injured

A blaze raced through a crowded nightclub in southern Brazil early Sunday, killing 232 people as the air filled with deadly smoke and panicked party-goers stampeded toward the exits, police and witnesses said. It appeared to be the world's deadliest nightclub fire in more than a decade.

Witnesses said that a flare or firework lit by band members may have started the fire.

Police Maj. Cleberson Braida Bastianello said by telephone that officials counted 232 bodies that had been brought for identification to a gymnasium in the city of Santa Maria, at the southern tip of Brazil near the borders with Argentina and Uruguay.

Another 117 people were being treated at hospitals, he said, and President Dilma Roussef arrived to visit victims after cutting short participation at a Latin American-European summit in Chile.

Bastianello said the recount lowered the toll from 245 earlier believed killed.

Television images showed smoke pouring out of the Kiss nightclub as shirtless, young male partygoers joined firefighters in wielding axes and sledgehammers, pounding at windows and walls to break through to those trapped inside. Teenagers sprinted from the scene desperately trying to find help. Others carried injured and burned friends away in their arms.

"There was so much smoke and fire, it was complete panic and it took a long time for people to get out, there were so many dead," survivor Luana Santos Silva told the Globo TV network.

Germano Roratto/AFP/Getty Images

Silva added that firefighters and ambulances responded quickly after the fire broke out, but that it spread too fast inside the packed club for them to help.

Michele Pereira, another survivor, told the Folha de S. Paulo newspaper that she was near the stage and that the fire broke out after members of the band lit flares.

"The band that was onstage began to use flares and, suddenly, they stopped the show and pointed them upward. At that point the ceiling caught fire. It was really weak but in a matter of seconds it spread," Pereira said.

Most of the dead apparently suffocated, according to Dr. Paulo Afonso Beltrame, a professor at the medical school of the Federal University of Santa Maria who raced the city's Caridade Hospital to help victims.

He said survivors, police and firefighters told him a flare set off by a band member set the ceiling's soundproofing ablaze. "Large amounts of toxic smoke quickly filled the room and I would say that at least 90 percent of the victims died of asphyxiation," Beltrame told The Associated Press by telephone.

"The toxic smoke made people lose their sense of direction so they were unable to find their way to the exit. At least 50 bodies were found inside a bathroom. Apparently they confused the bathroom door with the exit door."

"In the hospital I saw desperate friends and relatives walking and running down the corridors looking for information. It was one of the saddest scenes I have ever witnessed," he added.

Rodrigo Moura, identified by the newspaper Diario de Santa Maria as a security guard at the club, said it was at its maximum capacity of between 1,000 and 2,000, and partygoers were pushing and shoving to escape.

Beltrame also said he was told the club was filled far past its capacity during a party for students at the university's department of agronomy. The event featured a group called Gurizada Fandangueira, which plays a driving mixture of local Brazilian country music styles. It was not immediately clear if the band members were among the victims.

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Get cirrus in the fight against climate change

FEATHERY cirrus clouds are beautiful, but when it comes to climate change, they are the enemy. Found at high-altitude and made of small ice crystals, they trap heat - so more cirrus means a warmer world. Now it seems that, by destroying cirrus, we could reverse all the warming Earth has experienced so far.

In 2009, David Mitchell of the Desert Research Institute in Reno, Nevada, proposed a radical way to stop climate change: get rid of some cirrus. Now Trude Storelvmo of Yale University and colleagues have used a climate model to test the idea.

Storelvmo added powdered bismuth triiodide into the model's troposphere, the layer of the atmosphere in which these clouds form. Ice crystals grew around these particles and expanded, eventually falling out of the sky, reducing cirrus coverage. Without the particles, the ice crystals remained small and stayed up high for longer.

The technique, done on a global scale, created a powerful cooling effect, enough to counteract the 0.8 °C of warming caused by all the greenhouse gases released by humans (Geophysical Research Letters, DOI: 10.1002/grl.50122).

But too much bismuth triiodide made the ice crystals shrink, so cirrus clouds lasted longer. "If you get the concentrations wrong, you could get the opposite of what you want," says Storelvmo. And, like other schemes for geoengineering, side effects are likely - changes in the jet stream, say.

Different model assumptions give different "safe" amounts of bismuth triiodide, says Tim Lenton of the University of Exeter, UK. "Do we really know the system well enough to be confident of being in the safe zone?" he asks. "You wouldn't want to touch this until you knew."

Mitchell says seeding would take 140 tonnes of bismuth triiodide every year, which by itself would cost $19 million.

If you would like to reuse any content from New Scientist, either in print or online, please contact the syndication department first for permission. New Scientist does not own rights to photos, but there are a variety of licensing options available for use of articles and graphics we own the copyright to.

All comments should respect the New Scientist House Rules. If you think a particular comment breaks these rules then please use the "Report" link in that comment to report it to us.

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10 police killed in Afghanistan suicide attack: official

KABUL: At least 10 policemen were killed and 18 others, mostly civilians, were wounded in a suicide attack Saturday in a crowded area of the northeast Afghan city of Kunduz, provincial authorities said.

The attacker, who was on foot, detonated his explosives next to a group of police officers, according to several sources.

"We have 10 dead, including the counter terrorism police chief and head of traffic police and their bodyguards," Sayed Sarwar Hussani, Kunduz police spokesman told AFP.

Thirteen civilians and five policemen were wounded in the blast, Hussani said, adding that the final death toll may rise.

The attack was "the work of the enemies of Afghanistan", he said, using a phrase common among Afghan officials to describe Taliban insurgents.

AFP could not immediately reach the Taliban for comment on the attack, which has so far not been claimed by any group.

Afghanistan's interior ministry and the provincial governor spokesman Enayatullah Khaleeq confirmed the toll.

According to the head of the Kunduz health department, Saad Mukhtar, 19 people in total were wounded in the attack, which police officials said took place around 5:20 pm, 12:50 GMT.

Such attacks have in the past been blamed on Taliban insurgents who are leading an 11-year insurgency against the US-backed government of President Hamid Karzai.

Taliban militants have stepped up their fight against Afghan troops as the country's forces are increasingly taking over security responsibility from US-led NATO troops.

Earlier Saturday, a suicide attacker on a bicycle killed two civilians in southeastern Afghanistan's Ghazni province, and on Friday a suicide bomber in a car attacked a NATO convoy in Afghanistan's strategic Kapisa province, killing at least five civilians and wounding 15 others.

Also this week a squad of Taliban suicide bombers attacked Kabul traffic police headquarters in the heart of the city, killing three police officers and wounding dozens others.

The attacks come at a crucial juncture for Afghanistan as US-led NATO troops are preparing for their withdrawal from the country by the end of 2014. Afghan and international observers have predicted a civil war could grip the country once foreign troops have pulled out.

- AFP/jc

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Oppo BDP-105: Not your average Blu-ray player

The Oppo BDP-105 Blu-ray, SACD, and DVD-Audio player

(Credit:
Oppo)

Even by Oppo's high standards the BDP-105 is an extraordinary Blu-ray player. Sure, it's loaded with up-to-the-second features -- 4K upscaling, 2D-to-3D conversion, and a high-quality USB 2.0 digital-to-analog converter -- but what really makes the Oppo special is the sound. Pop the cover and look inside and you'll see why. Most of the 17-pound component's chassis space is devoted to the audio circuitry. That's nice, but the audio advantages will be completely irrelevant if you connect the BDP-105 to your receiver with a HDMI cable (the digital-to-analog conversion would then be handled in the receiver). The 105 was designed for buyers still using older $1,000 or $2,000 receivers from the days before HDMI connectivity, that would like to hear the Blu-rays' high-resolution DTS Master Audio or Dolby TrueHD soundtracks at their best. Since the audio won't be transmitted over the HDMI cable, you would run audio cables between the 105's seven- or five-channel analog outputs and the AV receiver's analog inputs.

The BDP-105 has 7.1/5.1 analog output jacks

(Credit:
Steve Guttenberg/CNET)

Or you could forgo the receiver entirely and hook up the BDP-105 directly to a five- or seven-channel power amplifier. That approach would produce better sound quality, but would lack the connectivity, flexibility, and convenience of today's better receivers. Still, the BDP-105/power amp combo would sound better and be more powerful than most top-of-the-line receivers. The 105's connectivity options won't match any decent receiver, but its connectivity suite is a lot more extensive than most Blu-ray players. The Oppo has two HDMI inputs, so you can connect external devices such as set-top boxes and network streaming devices, three USB 2.0 ports, coaxial and optical digital inputs for satellite boxes, televisions, video-game consoles, etc., and there's a built-in headphone amplifier. The BDP-105's extensive bass management options are on par with a lot of AV receivers. The player's digital volume control is easy to use.

For my listening tests, I hooked up the BDP-105 ($1,199) with an assortment of self-powered Audioengine and Emotiva monitor speakers, and a Hsu subwoofer. With this setup I didn't need to use an AV receiver or separate power amp, but the Raconteurs' "Live at Montreux" Blu-ray was vivid and very live sounding. The system's freewheeling dynamics were really impressive, and the surround mix on King Crimson's "Red" DVD-A projected a remarkably seamless wrap-around soundstage. Each instrument was precisely focused in a near 360-degree sound environment.

The BDP-105 has full speaker setup and bass management options, just like an AV receiver.

(Credit:
Steve Guttenberg/CNET)

Classical music on SACD was just as impressive, the front three speakers produced a three-dimensional soundstage with lots of depth, and string tone was top notch. Dramatic movies on Blu-ray and DVD sounded great. I plugged headphones into the BDP-105, but the sound wasn't special, Schiit Audio's $99 Magni headphone amp was a lot better.

The $499 Oppo BDP-103 shares most of the BDP-105's features, but lacks the upgraded digital-to-analog converters, so if you're planning on using HDMI to connect the player to your receiver, buy the 103, and save $700. You can use the 103's 7.1 analog outputs with an old high-end receiver lacking HDMI connectivity, but the 103's digital converters are a step down from the ones in the 105.

The BDP-105 is an update of the Oppo BDP-95, and the new one has lots of features the old player lacks, but the two players sound about the same. Oppo still has 95s in stock and sells them for $799.

Oppo sells direct and offers a 30-day money-back guarantee, and the return shipping is free.

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Pictures: The Story Behind Sun Dogs, Penitent Ice, and More

Photograph by Art Wolfe, Getty Images

If you want the beauty of winter without having to brave the bone-chilling temperatures blasting much of the United States this week, snuggle into a soft blanket, grab a warm beverage, and curl up with some of these natural frozen wonders.

Nieve penitente, or penitent snow, are collections of spires that resemble robed monks—or penitents. They are flattened columns of snow wider at the base than at the tip and can range in height from 3 to 20 feet (1 to 6 meters). The picture above shows the phenomenon in central Chile. (See pictures of the patterns in snow and ice.)

Nieve penitente tend to form in shallow valleys where the snow is deep and the sun doesn't shine at too steep an angle, said Kenneth Libbrecht, a physicist at the California Institute of Technology in Pasadena who studies ice crystal formation.

As the snow melts, dirt gets mixed in with the runoff and collects in little pools here and there, he said. Since the dirt is darker in color than the surrounding snow, the dirty areas melt faster "and you end up digging these pits," explained Libbrecht.

"They tend to form at high altitude," he said. But other than that, no one really knows the exact conditions that are needed to form penitent snow.

"They're fairly strong," Libbrecht said. "People have found [the spires] difficult to hike through."

—Jane J. Lee

Published January 25, 2013

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Cops Using More Private Cameras to Nab Suspects

Philadelphia detectives were able to quickly make an arrest in the murder and burning of a female pediatrician by viewing surveillance video of nearby stores and a hospital that captured the suspect entering the doctor's home and later getting into his truck.

In the hours after Dr. Melissa Ketunuti's body was found strangled and burning in her basement, city's Homicide Task Force collected surveillance footage from a coffee shop, drug store and hospital overlooking Ketunuti's block. It was footage taken from Ori Feibush's coffee shop that allowed cops to identify Smith.

The suspect, an exterminator named Jason Smith, soon confessed to detectives, police said.

Lately a range of crimes have been solved by the seemingly ubiquitous security videos maintained by private companies or citizens, and investigators have been able to quickly apprehend suspects by obtaining the video, deftly turning private cameras into effective police resources.

Philadelphia Police Arrest Suspect in Doctor's Killing Watch Video

Pa. Doctor Killing: Person of Interest in Custody Watch Video

Private surveillance cameras have become so pervasive that the face of a suspect who allegedly shot a Bronx, N.Y., cab driver in a botched robbery on Jan. 14 was splashed throughout the media within days because the cabbie had rigged his vehicle with a camera.

The New York Police Department arrested Salvatore Perrone after he was caught on surveillance video recorded near two of three shopkeeper slayings in Brooklyn, N.Y., in November. He has since been charged with murder.

And in Mesa, Ariz., surveillance footage taken in November by resident Mitch Drum showed a man rolling on the ground trying to extinguish flames that had engulfed his shirt, which had caught fire while he was allegedly siphoning gas from a car by Drum's house. The man was arrested.

Though surveillance cameras have been a staple of security since a network of government operated cameras dubbed the "ring of steel" was introduced in London in the early 1990s, police have recently launched programs to partner with more businesses.

In Philadelphia, police have launched a program for businesses to register private cameras with the department. According to the SafeCam website, businesses will only be contacted when there is a criminal incident in the vicinity of the security camera. At that point, police will request a copy of the footage for their investigation.

"Businesses are saying, 'I have a camera at this location, and it may or may not be of use to you. It's a registration to say, 'feel free to call me,'" Sgt. Joseph Green told ABCNews.com

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